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Chiral Dihydrobenzofuran Acids Show Potent Retinoid X Receptor-Nuclear Receptor Related 1 Protein Dimer Activation.
Sundén, Henrik; Schäfer, Anja; Scheepstra, Marcel; Leysen, Seppe; Malo, Marcus; Ma, Jian-Nong; Burstein, Ethan S; Ottmann, Christian; Brunsveld, Luc; Olsson, Roger.
Afiliación
  • Sundén H; Department of Chemistry and Molecular Biology, Medicinal Chemistry, University of Gothenburg , SE-41296 Gothenburg, Sweden.
  • Schäfer A; Department of Chemistry and Molecular Biology, Medicinal Chemistry, University of Gothenburg , SE-41296 Gothenburg, Sweden.
  • Scheepstra M; Department of Biomedical Engineering and Institute of Complex Molecular Systems, Laboratory of Chemical Biology, Technische Universiteit Eindhoven , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
  • Leysen S; Department of Biomedical Engineering and Institute of Complex Molecular Systems, Laboratory of Chemical Biology, Technische Universiteit Eindhoven , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
  • Malo M; Department of Biomedical Engineering and Institute of Complex Molecular Systems, Laboratory of Chemical Biology, Technische Universiteit Eindhoven , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
  • Ma JN; Department of Chemistry and Molecular Biology, Medicinal Chemistry, University of Gothenburg , SE-41296 Gothenburg, Sweden.
  • Burstein ES; ACADIA Pharmaceuticals Inc. , San Diego, California 92130, United States.
  • Ottmann C; ACADIA Pharmaceuticals Inc. , San Diego, California 92130, United States.
  • Brunsveld L; Department of Biomedical Engineering and Institute of Complex Molecular Systems, Laboratory of Chemical Biology, Technische Universiteit Eindhoven , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
  • Olsson R; Department of Biomedical Engineering and Institute of Complex Molecular Systems, Laboratory of Chemical Biology, Technische Universiteit Eindhoven , Den Dolech 2, 5612 AZ Eindhoven, The Netherlands.
J Med Chem ; 59(3): 1232-8, 2016 Feb 11.
Article en En | MEDLINE | ID: mdl-26820900
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Benzofuranos / Receptores X Retinoide / Multimerización de Proteína / Miembro 2 del Grupo A de la Subfamilia 4 de Receptores Nucleares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Suecia
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Benzofuranos / Receptores X Retinoide / Multimerización de Proteína / Miembro 2 del Grupo A de la Subfamilia 4 de Receptores Nucleares Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2016 Tipo del documento: Article País de afiliación: Suecia