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Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.
Scekic-Zahirovic, Jelena; Sendscheid, Oliver; El Oussini, Hajer; Jambeau, Mélanie; Sun, Ying; Mersmann, Sina; Wagner, Marina; Dieterlé, Stéphane; Sinniger, Jérome; Dirrig-Grosch, Sylvie; Drenner, Kevin; Birling, Marie-Christine; Qiu, Jinsong; Zhou, Yu; Li, Hairi; Fu, Xiang-Dong; Rouaux, Caroline; Shelkovnikova, Tatyana; Witting, Anke; Ludolph, Albert C; Kiefer, Friedemann; Storkebaum, Erik; Lagier-Tourenne, Clotilde; Dupuis, Luc.
Afiliación
  • Scekic-Zahirovic J; Faculté de Médecine, INSERM U1118, Strasbourg, France Université de Strasbourg UMR_S1118, Strasbourg, France.
  • Sendscheid O; Molecular Neurogenetics Laboratory, Max Planck Institute for Molecular Biomedicine, Muenster, Germany Faculty of Medicine, University of Muenster, Muenster, Germany.
  • El Oussini H; Faculté de Médecine, INSERM U1118, Strasbourg, France Université de Strasbourg UMR_S1118, Strasbourg, France.
  • Jambeau M; Department of Neurosciences, University of California, San Diego La Jolla, CA, USA Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA, USA.
  • Sun Y; Department of Neurosciences, University of California, San Diego La Jolla, CA, USA Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA, USA.
  • Mersmann S; Molecular Neurogenetics Laboratory, Max Planck Institute for Molecular Biomedicine, Muenster, Germany Faculty of Medicine, University of Muenster, Muenster, Germany.
  • Wagner M; Molecular Neurogenetics Laboratory, Max Planck Institute for Molecular Biomedicine, Muenster, Germany Faculty of Medicine, University of Muenster, Muenster, Germany.
  • Dieterlé S; Faculté de Médecine, INSERM U1118, Strasbourg, France Université de Strasbourg UMR_S1118, Strasbourg, France.
  • Sinniger J; Faculté de Médecine, INSERM U1118, Strasbourg, France Université de Strasbourg UMR_S1118, Strasbourg, France.
  • Dirrig-Grosch S; Faculté de Médecine, INSERM U1118, Strasbourg, France Université de Strasbourg UMR_S1118, Strasbourg, France.
  • Drenner K; Department of Neurosciences, University of California, San Diego La Jolla, CA, USA Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA, USA.
  • Birling MC; Institut Clinique de la souris, Illkirch-Graffenstaden, France.
  • Qiu J; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Zhou Y; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Li H; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Fu XD; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, USA.
  • Rouaux C; Faculté de Médecine, INSERM U1118, Strasbourg, France Université de Strasbourg UMR_S1118, Strasbourg, France.
  • Shelkovnikova T; University of Cardiff, Cardiff, UK.
  • Witting A; Department of Neurology University of Ulm, Ulm, Germany.
  • Ludolph AC; Department of Neurology University of Ulm, Ulm, Germany.
  • Kiefer F; Mammalian Cell Signaling Laboratory, Department of Vascular Cell Biology, Max Planck Institute for Molecular Biomedicine, Muenster, Germany.
  • Storkebaum E; Molecular Neurogenetics Laboratory, Max Planck Institute for Molecular Biomedicine, Muenster, Germany Faculty of Medicine, University of Muenster, Muenster, Germany erik.storkebaum@mpi-muenster.mpg.de clagier-tourenne@mgh.harvard.edu ldupuis@unistra.fr.
  • Lagier-Tourenne C; Department of Neurosciences, University of California, San Diego La Jolla, CA, USA Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, CA, USA erik.storkebaum@mpi-muenster.mpg.de clagier-tourenne@mgh.harvard.edu ldupuis@unistra.fr.
  • Dupuis L; Faculté de Médecine, INSERM U1118, Strasbourg, France Université de Strasbourg UMR_S1118, Strasbourg, France erik.storkebaum@mpi-muenster.mpg.de clagier-tourenne@mgh.harvard.edu ldupuis@unistra.fr.
EMBO J ; 35(10): 1077-97, 2016 05 17.
Article en En | MEDLINE | ID: mdl-26951610
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteína FUS de Unión a ARN / Neuronas Motoras Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: EMBO J Año: 2016 Tipo del documento: Article País de afiliación: Francia
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteína FUS de Unión a ARN / Neuronas Motoras Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: EMBO J Año: 2016 Tipo del documento: Article País de afiliación: Francia