Impedance Analysis of Colloidal Gold Nanoparticles in Chromatography Paper for Quantitation of an Immunochromatographic Assay.
Anal Sci
; 32(3): 355-9, 2016.
Article
en En
| MEDLINE
| ID: mdl-26960618
ABSTRACT
A detection method of gold nanoparticles in chromatography paper has been developed for a simple, cost-effective and reliable quantitation of immunochromatographic strip test. The time courses of the solution resistance in chromatography paper with the gold nanoparticles solution are electrochemically measured by chrono-impedimetry. The dependence of the solution resistance on the concentration of gold nanoparticles has been successfully observed. The main factor to increase the solution resistance may be obstruction of the ion transport due to the presence of gold nanoparticles. The existence of gold nanoparticles with 1.92 × 10(9) particles/mL in an indistinctly-colored chromatography paper is also identified by a solution resistance measurement. This indicates that the solution resistance assay has the potential to lower the detection limit of the conventional qualitative assay.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Cromatografía de Afinidad
/
Cromatografía en Papel
/
Impedancia Eléctrica
/
Coloides
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Nanopartículas del Metal
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Oro
Tipo de estudio:
Prognostic_studies
/
Qualitative_research
Idioma:
En
Revista:
Anal Sci
Año:
2016
Tipo del documento:
Article