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Acneiform Rash Induced by EGFR Inhibitors: Review of the Literature and New Insights.
Fabbrocini, Gabriella; Panariello, Luigia; Caro, Gemma; Cacciapuoti, Sara.
Afiliación
  • Fabbrocini G; Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
  • Panariello L; Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
  • Caro G; Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
  • Cacciapuoti S; Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
Skin Appendage Disord ; 1(1): 31-7, 2015 Mar.
Article en En | MEDLINE | ID: mdl-27171241
ABSTRACT
Acneiform rash is the most common side effect of epidermal growth factor receptor (EGFR) inhibitors (EGFRis), and it occurs in 50-100% of patients. This condition can affect the quality of life of these patients and can sometimes lead to a discontinuation of the antineoplastic therapy. Several recent prospective studies have addressed and evaluated different interventions to mitigate or reduce the severity of EGFRis-associated skin rash. With this aim, we have established a dermocosmetological outpatient clinic for cancer patients at the Department of Clinical Medicine and Surgery, University of Naples Federico II in collaboration with the Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami. An interdisciplinary network of physicians can improve the quality of life of the cancer patients, focusing on such important aspects as dermocosmetological skin care, but also on the evaluation of new therapeutic and diagnostic algorithms in order to make further progress in the field of prevention. In this review, we summarize the state of the art of the epidemiology, pathogenesis, and treatment of EGFRis acneiform rash, and we describe our outpatient clinical experience.
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Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: Skin Appendage Disord Año: 2015 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Bases de datos: MEDLINE Tipo de estudio: Observational_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: Skin Appendage Disord Año: 2015 Tipo del documento: Article País de afiliación: Italia