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Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer's disease neurons.
van den Bos, Hilda; Spierings, Diana C J; Taudt, Aaron S; Bakker, Bjorn; Porubský, David; Falconer, Ester; Novoa, Carolina; Halsema, Nancy; Kazemier, Hinke G; Hoekstra-Wakker, Karina; Guryev, Victor; den Dunnen, Wilfred F A; Foijer, Floris; Tatché, Maria Colomé; Boddeke, Hendrikus W G M; Lansdorp, Peter M.
Afiliación
  • van den Bos H; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Spierings DC; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Taudt AS; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Bakker B; Institute for Computational Biology, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
  • Porubský D; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Falconer E; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Novoa C; Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, V5Z 1 L3, Canada.
  • Halsema N; Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, V5Z 1 L3, Canada.
  • Kazemier HG; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Hoekstra-Wakker K; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Guryev V; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • den Dunnen WF; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Foijer F; Section of Pathology, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Tatché MC; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Boddeke HW; European Research Institute for the Biology of Ageing (ERIBA), University of Groningen, University Medical Center Groningen, 9713 AV, Groningen, The Netherlands.
  • Lansdorp PM; Institute for Computational Biology, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Genome Biol ; 17(1): 116, 2016 05 31.
Article en En | MEDLINE | ID: mdl-27246599
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Genoma Humano / Análisis de Secuencia de ADN / Análisis de la Célula Individual / Enfermedad de Alzheimer / Aneuploidia / Neuronas Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Genome Biol Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Genoma Humano / Análisis de Secuencia de ADN / Análisis de la Célula Individual / Enfermedad de Alzheimer / Aneuploidia / Neuronas Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Genome Biol Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos