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Development of SYN-004, an oral beta-lactamase treatment to protect the gut microbiome from antibiotic-mediated damage and prevent Clostridium difficile infection.
Kaleko, Michael; Bristol, J Andrew; Hubert, Steven; Parsley, Todd; Widmer, Giovanni; Tzipori, Saul; Subramanian, Poorani; Hasan, Nur; Koski, Perrti; Kokai-Kun, John; Sliman, Joseph; Jones, Annie; Connelly, Sheila.
Afiliación
  • Kaleko M; Synthetic Biologics, Inc., Rockville, MD, USA. Electronic address: mkaleko@syntheticbiologics.com.
  • Bristol JA; Synthetic Biologics, Inc., Rockville, MD, USA.
  • Hubert S; Synthetic Biologics, Inc., Rockville, MD, USA.
  • Parsley T; SynPhaGen, LLC, Rockville, MD, USA.
  • Widmer G; Tufts Cummings School of Veterinary Medicine, North Grafton, MA, USA.
  • Tzipori S; Tufts Cummings School of Veterinary Medicine, North Grafton, MA, USA.
  • Subramanian P; CosmosID, Inc., Rockville, MD, USA.
  • Hasan N; CosmosID, Inc., Rockville, MD, USA.
  • Koski P; Ipsat Therapies, Helsinki, Finland (closed 2011).
  • Kokai-Kun J; Synthetic Biologics, Inc., Rockville, MD, USA.
  • Sliman J; Synthetic Biologics, Inc., Rockville, MD, USA.
  • Jones A; Synthetic Biologics, Inc., Rockville, MD, USA.
  • Connelly S; Synthetic Biologics, Inc., Rockville, MD, USA.
Anaerobe ; 41: 58-67, 2016 Oct.
Article en En | MEDLINE | ID: mdl-27262694
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Beta-Lactamasas / Proteínas Recombinantes / Enterocolitis Seudomembranosa / Microbioma Gastrointestinal / Antibacterianos Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Anaerobe Año: 2016 Tipo del documento: Article
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Beta-Lactamasas / Proteínas Recombinantes / Enterocolitis Seudomembranosa / Microbioma Gastrointestinal / Antibacterianos Tipo de estudio: Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: Anaerobe Año: 2016 Tipo del documento: Article