Aquaporins in Urinary Extracellular Vesicles (Exosomes).
Int J Mol Sci
; 17(6)2016 Jun 17.
Article
en En
| MEDLINE
| ID: mdl-27322253
ABSTRACT
Since the successful characterization of urinary extracellular vesicles (uEVs) by Knepper's group in 2004, these vesicles have been a focus of intense basic and translational research worldwide, with the aim of developing novel biomarkers and therapeutics for renal disease. Along with these studies, there is growing evidence that aquaporins (AQPs), water channel proteins, in uEVs have the potential to be diagnostically useful. In this review, we highlight current knowledge of AQPs in uEVs from their discovery to clinical application.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Acuaporinas
/
Exosomas
/
Enfermedades Renales
Límite:
Humans
Idioma:
En
Revista:
Int J Mol Sci
Año:
2016
Tipo del documento:
Article
País de afiliación:
Japón