Possible Epithelial Ovarian Cancer Association with HPV18 or HPV33 Infection.
Asian Pac J Cancer Prev
; 17(6): 2959-64, 2016.
Article
en En
| MEDLINE
| ID: mdl-27356718
ABSTRACT
The present study was conducted to investigate the prevalence of HPV infection in epithelial ovarian cancer (EOC) in Hunan province. DNA samples were collected from paraffin embedded ovarian tissue from 322 patients with EOC, 99 with ovarian benign tumors and 199 normal persons. The polymerase chain reaction and direct sequencing were used to identify the HPV types in the samples. The relationship between the infection of human papillomavirus (HPV) and the epithelial ovarian carcinoma (EOC) was investigated combined with clinical data. The prevalence of HPV18 and HPV33 in EOC group and benign group was higher than in the normal group. HPV18 and HPV33 may play a role in the development of both EOC and ovarian benign tumor and may participate in the development of EOC with traditional risk factors, family history and abortion, possibly exerting synergistic effects..
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Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
/
Papillomaviridae
/
Neoplasias Glandulares y Epiteliales
/
Infecciones por Papillomavirus
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Asian Pac J Cancer Prev
Asunto de la revista:
NEOPLASIAS
Año:
2016
Tipo del documento:
Article