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Unique quadruple immunofluorescence assay demonstrates mitochondrial respiratory chain dysfunction in osteoblasts of aged and PolgA(-/-) mice.
Dobson, Philip F; Rocha, Mariana C; Grady, John P; Chrysostomou, Alexia; Hipps, Daniel; Watson, Sharon; Greaves, Laura C; Deehan, David J; Turnbull, Doug M.
Afiliación
  • Dobson PF; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
  • Rocha MC; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
  • Grady JP; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
  • Chrysostomou A; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
  • Hipps D; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
  • Watson S; Musculoskeletal Research Group, Medical School, Newcastle University, United Kingdom.
  • Greaves LC; Wellcome Trust Centre for Mitochondrial Research, Institute for Neuroscience, Medical School, Newcastle University, United Kingdom.
  • Deehan DJ; MRC/BBSRC Centre for Ageing and Vitality, Newcastle University, United Kingdom.
  • Turnbull DM; Institute of Cellular Medicine, Newcastle University, United Kingdom.
Sci Rep ; 6: 31907, 2016 08 24.
Article en En | MEDLINE | ID: mdl-27553587
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Osteoblastos / Osteoporosis / Envejecimiento / Proteínas del Complejo de Cadena de Transporte de Electrón / ADN Polimerasa gamma Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Osteoblastos / Osteoporosis / Envejecimiento / Proteínas del Complejo de Cadena de Transporte de Electrón / ADN Polimerasa gamma Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido