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Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers.
Goldstein, Leonard D; Lee, James; Gnad, Florian; Klijn, Christiaan; Schaub, Annalisa; Reeder, Jens; Daemen, Anneleen; Bakalarski, Corey E; Holcomb, Thomas; Shames, David S; Hartmaier, Ryan J; Chmielecki, Juliann; Seshagiri, Somasekar; Gentleman, Robert; Stokoe, David.
Afiliación
  • Goldstein LD; Department of Molecular Biology, Genentech Inc., South San Francisco, CA 94080, USA; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Lee J; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Gnad F; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Klijn C; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Schaub A; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Reeder J; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Daemen A; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Bakalarski CE; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA; Department of Protein Chemistry, Genentech Inc., South San Francisco, CA 94080, USA.
  • Holcomb T; Department of Oncology Biomarker Development, Genentech Inc., South San Francisco, CA 94080, USA.
  • Shames DS; Department of Oncology Biomarker Development, Genentech Inc., South San Francisco, CA 94080, USA.
  • Hartmaier RJ; Foundation Medicine Inc., Cambridge, MA 02141, USA.
  • Chmielecki J; Foundation Medicine Inc., Cambridge, MA 02141, USA.
  • Seshagiri S; Department of Molecular Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Gentleman R; Department of Bioinformatics and Computational Biology, Genentech Inc., South San Francisco, CA 94080, USA.
  • Stokoe D; Department of Discovery Oncology, Genentech Inc., South San Francisco, CA 94080, USA. Electronic address: stokoe.david@gene.com.
Cell Rep ; 16(10): 2605-2617, 2016 09 06.
Article en En | MEDLINE | ID: mdl-27568559
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transducción de Señal / Exones / Factor 2 Relacionado con NF-E2 / Mutación / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Transducción de Señal / Exones / Factor 2 Relacionado con NF-E2 / Mutación / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Cell Rep Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos