Fetal growth and air pollution - A study on ultrasound and birth measures.
Environ Res
; 152: 73-80, 2017 Jan.
Article
en En
| MEDLINE
| ID: mdl-27741452
ABSTRACT
Air pollution has been suggested to affect fetal growth, but more data is needed to assess the timing of exposure effects by using ultrasound measures. It is also important to study effects in low exposure areas to assess eventual thresholds of effects. The MAPSS (Maternal Air Pollution in Southern Sweden) cohort consists of linked registry data for around 48,000 pregnancies from an ultrasound database, birth registry and exposure data based on residential addresses. Measures of air pollution exposure were obtained through dispersion modelling with input data from an emissions database (NOx) with high resolution (100-500m grids). Air pollution effects were assessed with linear regressions for the following endpoints; biparietal diameter, femur length, abdominal diameter and estimated fetal weight measured in late pregnancy and birth weight and head circumference measured at birth. We estimated negative effects for NOx; in the adjusted analyses the decrease of abdominal diameter and femur length were -0.10 (-0.17, -0.03) and -0.13 (-0.17, -0.01)mm, respectively, per 10µg/m3 increment of NOx. We also estimated an effect of NOx-exposures on birth weight by reducing birth weight by 9g per 10µg/m3 increment of NOx. We estimated small but statistically significant effects of air pollution on late fetal and birth size and reduced fetal growth late in pregnancy in a geographic area with levels below current WHO air quality guidelines.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Emisiones de Vehículos
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Exposición Materna
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Desarrollo Fetal
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Contaminantes Atmosféricos
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Exposición a Riesgos Ambientales
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Feto
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Óxidos de Nitrógeno
Tipo de estudio:
Diagnostic_studies
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Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Female
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Humans
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Male
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Pregnancy
País/Región como asunto:
Europa
Idioma:
En
Revista:
Environ Res
Año:
2017
Tipo del documento:
Article