Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity <i>in vitro</i> and <i>in vivo</i> against chronic lymphocytic leukemia.

Vyas, Maulik; Schneider, Ann-Charlott; Shatnyeva, Olga; Reiners, Katrin S; Tawadros, Samir; Kloess, Stephan; Köhl, Ulrike; Hallek, Michael; Hansen, Hinrich P; Pogge von Strandmann, Elke

Mono- and dual-targeting triplebodies activate natural killer cells and have anti-tumor activity in vitro and in vivo against chronic lymphocytic leukemia.

Vyas, Maulik; Schneider, Ann-Charlott; Shatnyeva, Olga; Reiners, Katrin S; Tawadros, Samir; Kloess, Stephan; Köhl, Ulrike; Hallek, Michael; Hansen, Hinrich P; Pogge von Strandmann, Elke.

Afiliación

Vyas M; Department I of Internal Medicine, University Hospital of Cologne , Cologne, Germany.
Schneider AC; Department I of Internal Medicine, University Hospital of Cologne , Cologne, Germany.
Shatnyeva O; Department I of Internal Medicine, University Hospital of Cologne , Cologne, Germany.
Reiners KS; Department I of Internal Medicine, University Hospital of Cologne , Cologne, Germany.
Tawadros S; Department of Experimental Medicine, University Hospital of Cologne , Cologne, Germany.
Kloess S; Institute of Cellular Therapeutics, IFB-Tx, Hannover Medical School , Hannover, Germany.
Köhl U; Institute of Cellular Therapeutics, IFB-Tx, Hannover Medical School , Hannover, Germany.
Hallek M; Department I of Internal Medicine, University Hospital of Cologne , Cologne, Germany.
Hansen HP; Department I of Internal Medicine, University Hospital of Cologne , Cologne, Germany.
Pogge von Strandmann E; Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany; Experimental Tumor Research, Center for Tumor Biology and Immunology, Philipps University Marburg, Marburg, Germany.

Oncoimmunology ; 5(9): e1211220, 2016.

Article en En | MEDLINE | ID: mdl-27757305

Palabras clave

CD19; CLL; NK cells; NKG2D; ULBP2; immunoligand; triplebody

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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: Oncoimmunology Año: 2016 Tipo del documento: Article País de afiliación: Alemania