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An inhibitor of apoptosis protein antagonist T-3256336 potentiates the antitumor efficacy of the Nedd8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924).
Sumi, Hiroyuki; Inazuka, Masakazu; Morimoto, Megumi; Hibino, Ryosuke; Hashimoto, Kentaro; Ishikawa, Tomoyasu; Kuida, Keisuke; Smith, Peter G; Yoshida, Sei; Yabuki, Masato.
Afiliación
  • Sumi H; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan. Electronic address: hiroyuki.sumi@takeda.com.
  • Inazuka M; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Morimoto M; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Hibino R; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Hashimoto K; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Ishikawa T; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Kuida K; Discovery, Millennium Pharmaceuticals, Inc., Cambridge, MA, 02139, USA.
  • Smith PG; Discovery, Millennium Pharmaceuticals, Inc., Cambridge, MA, 02139, USA.
  • Yoshida S; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan.
  • Yabuki M; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Ltd., 26-1, Muraoka-higashi, 2-Chome, Fujisawa, Kanagawa, 251-8555, Japan. Electronic address: masato.yabuki@takeda.com.
Biochem Biophys Res Commun ; 480(3): 380-386, 2016 Nov 18.
Article en En | MEDLINE | ID: mdl-27771247
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oligopéptidos / Pirazinas / Pirimidinas / Ubiquitinas / Protocolos de Quimioterapia Combinada Antineoplásica / Ciclopentanos / Proteínas Inhibidoras de la Apoptosis / Neoplasias Experimentales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2016 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oligopéptidos / Pirazinas / Pirimidinas / Ubiquitinas / Protocolos de Quimioterapia Combinada Antineoplásica / Ciclopentanos / Proteínas Inhibidoras de la Apoptosis / Neoplasias Experimentales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2016 Tipo del documento: Article