Assessing the effects of threonyl-tRNA synthetase on angiogenesis-related responses.
Methods
; 113: 132-138, 2017 01 15.
Article
en En
| MEDLINE
| ID: mdl-27847344
ABSTRACT
Several recent reports have found a connection between specific aminoacyl-tRNA synthetases and the regulation of angiogenesis. As this new area of research is explored, it is important to have reliable assays to assess the specific angiogenesis functions of these enzymes. This review provides information about specific in vitro and in vivo methods that were used to assess the angiogenic functions of threonyl-tRNA synthetase including endothelial cell migration and tube assays as well as chorioallantoic membrane and tumor vascularization assays. The theory and discussion include best methods of analysis and quantification along with the advantages and limitations of each type of assay.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Neoplasias Ováricas
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Treonina-ARNt Ligasa
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Bioensayo
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Membrana Corioalantoides
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Aminoacilación de ARN de Transferencia
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Inhibidores Enzimáticos
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Neovascularización Patológica
Idioma:
En
Revista:
Methods
Asunto de la revista:
BIOQUIMICA
Año:
2017
Tipo del documento:
Article
País de afiliación:
Estados Unidos