CASE OF METASTATIC UROTHELIAL CARCINOMA OF THE RETINA AND VITREOUS.
Retin Cases Brief Rep
; 12(3): 177-180, 2018.
Article
en En
| MEDLINE
| ID: mdl-27930437
ABSTRACT
PURPOSE:
To report a rare case of vitreo-retinal metastasis from urothelial carcinoma of the bladder.METHODS:
Case report.RESULTS:
A 55-year-old man with a history of bladder cancer developed atypical vitritis and a white fundus mass. Intravenous fluorescein angiography demonstrated connection between the retinal and tumor vasculature consistent with a retinal malignancy. Cytologic analysis of the vitreous sample revealed large, atypical cells with pleomorphic nuclei, mucin vacuoles, and rare mitotic figures. The cells were immunoreactive for cytokeratin markers AE1/AE3, CK7, and CK20 and the urothelial carcinoma marker GATA3. Review of the patient's initial bladder tumor revealed an anaplastic epithelial neoplasm with dyscohesive cells that appeared histologically identical to those in the vitreous biopsy. Despite external beam radiation therapy, the patient's vision declined and the eye became painful and was ultimately enucleated.CONCLUSION:
Retinal metastasis from systemic adenocarcinoma is an extremely rare occurrence with poor prognosis for vision.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Cuerpo Vítreo
/
Neoplasias de la Vejiga Urinaria
/
Adenocarcinoma
/
Neoplasias de la Retina
Tipo de estudio:
Prognostic_studies
Límite:
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Retin Cases Brief Rep
Año:
2018
Tipo del documento:
Article