Methotrexate Use and Monitoring in Patients with Psoriasis: A Consensus Report Based on a Danish Expert Meeting.
Acta Derm Venereol
; 97(4): 426-432, 2017 Apr 06.
Article
en En
| MEDLINE
| ID: mdl-27958611
ABSTRACT
Methotrexate (MTX) has been used in the treatment of psoriasis and other dermatological diseases for more than 50 years. However, there is limited evidence regarding its effect, dose and monitoring, and a lack of consensus regarding how the drug should be used in daily practice. Although the use of MTX is governed by guidelines, such as the European S3-Guidelines and the National Institute for Health and Care Excellence (NICE) guideline, it is important to discuss and adjust these guidelines to national standards. An expert meeting was held in Denmark at the end of 2014, in order to reach consensus regarding the use of MTX in dermatological practice in Denmark. Participants included dermatologists, hepatologists, paediatricians, clinical biochemists and a rheumatologist. Topics discussed were liver disease monitoring, teratogenic effects of MTX, risk of cancer, and use of MTX in children. We report here the conclusions of this expert meeting regarding use of MTX in dermatological practice.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Psoriasis
/
Metotrexato
/
Dermatología
/
Inmunosupresores
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Guideline
/
Risk_factors_studies
Límite:
Adult
/
Child
/
Female
/
Humans
/
Male
/
Pregnancy
País/Región como asunto:
Europa
Idioma:
En
Revista:
Acta Derm Venereol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Dinamarca