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Prevalence of alexithymia in patients with psoriasis and its association with disease burden: a multicentre observational study.
Sampogna, F; Puig, L; Spuls, P; Girolomoni, G; Radtke, M A; Kirby, B; Brunori, M; Bergmans, P; Smirnov, P; Rundle, J; Lavie, F; Paul, C.
Afiliación
  • Sampogna F; Dermatological Hospital IDI-IRCCS, Rome, Italy.
  • Puig L; Universitat Autònoma de Barcelona, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
  • Spuls P; Department of Dermatology, University of Amsterdam, Amsterdam, the Netherlands.
  • Girolomoni G; University of Verona, Verona, Italy.
  • Radtke MA; Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
  • Kirby B; St Vincent's University Hospital, Dublin, Ireland.
  • Brunori M; Janssen-Cilag, Paris, France.
  • Bergmans P; Janssen-Cilag BV, Tilburg, the Netherlands.
  • Smirnov P; Janssen Pharmaceutica NV, Moscow, Russia.
  • Rundle J; Janssen-Cilag Ltd, High Wycombe, Buckinghamshire, U.K.
  • Lavie F; Janssen-Cilag, Paris, France.
  • Paul C; Department of Dermatology, Toulouse University, Hôpital Larrey, 24 Chemin de Pouvourville, 31059, Toulouse, France.
Br J Dermatol ; 176(5): 1195-1203, 2017 05.
Article en En | MEDLINE | ID: mdl-27995617
BACKGROUND: Single-centre studies show that alexithymia, defined as difficulty in recognizing and describing emotions, is more prevalent among patients with psoriasis than in the general population. However, its prevalence and the consequences of the association between alexithymia and psoriasis are unclear. OBJECTIVES: The primary objective of this study was to determine the prevalence of alexithymia, as defined by a score ≥ 61 in the 20-item Toronto Alexithymia Scale, in a large sample of patients who had plaque psoriasis for ≤ 10 years and were eligible for phototherapy or systemic treatment. The secondary objectives were to investigate the relationship between alexithymia and the clinical and psychological aspects of psoriasis. METHODS: Data were collected in the framework of an observational, multicentre, international study, the EPidemiological Study In Patients With Recently DiagnosEd PSOriasis (EPIDEPSO), aiming at investigating the prevalence of alexithymia and other psychosocial comorbidities in patients with psoriasis of ≤ 10 years' disease duration. RESULTS: The prevalence of alexithymia within a cohort of 670 patients was 24·8% (95% confidence interval 21·7-28·2). Patients with alexithymia had a higher burden of psoriasis, including significant impairment of quality of life, higher levels of anxiety and depression, a higher risk of alcohol dependency and impairment of work productivity, compared with patients without alexithymia. CONCLUSIONS: It is important to identify alexithymic patients with psoriasis in clinical practice as they experience a higher disease burden and have a lower ability to express their feelings.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Psoriasis / Costo de Enfermedad / Síntomas Afectivos Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male País/Región como asunto: Africa / Europa Idioma: En Revista: Br J Dermatol Año: 2017 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Psoriasis / Costo de Enfermedad / Síntomas Afectivos Tipo de estudio: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male País/Región como asunto: Africa / Europa Idioma: En Revista: Br J Dermatol Año: 2017 Tipo del documento: Article País de afiliación: Italia