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mTORC1 activation downregulates FGFR3 and PTH/PTHrP receptor in articular chondrocytes to initiate osteoarthritis.
Zhang, H; Wang, H; Zeng, C; Yan, B; Ouyang, J; Liu, X; Sun, Q; Zhao, C; Fang, H; Pan, J; Xie, D; Yang, J; Zhang, T; Bai, X; Cai, D.
Afiliación
  • Zhang H; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: zhhy0704@126.com.
  • Wang H; State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China; Key Laboratory of Tropical Diseases and Translational Medicine of the Ministry of Education, Hainan Medical College, Haikou, China. Electronic
  • Zeng C; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: zengdavid@126.com.
  • Yan B; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: yanbosmu@gmail.com.
  • Ouyang J; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: oyjysmu029@126.com.
  • Liu X; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: liuxin_smu@sina.com.
  • Sun Q; State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China. Electronic address: Sunqiuyi2355287@163.com.
  • Zhao C; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: zhaochang81@126.com.
  • Fang H; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: fanghang@outlook.com.
  • Pan J; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: storm0132002@163.com.
  • Xie D; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: ste.ven.06@163.com.
  • Yang J; Academy of Orthopedics, General Hospital of Guangzhou Military Command of PLA, Guangzhou, China. Electronic address: gdgkyjc@126.com.
  • Zhang T; Academy of Orthopedics, General Hospital of Guangzhou Military Command of PLA, Guangzhou, China. Electronic address: gzlupus@126.com.
  • Bai X; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China; State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, C
  • Cai D; Academy of Orthopedics, Guangdong Province, Department of Orthopedics, The Third Affiliated Hospital, Southern Medical University, Guangzhou, China. Electronic address: daozhang@medmail.com.cn.
Osteoarthritis Cartilage ; 25(6): 952-963, 2017 06.
Article en En | MEDLINE | ID: mdl-28043938
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Osteoartritis / Cartílago Articular / Condrocitos / Osteoartritis de la Rodilla / Proteínas Supresoras de Tumor / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Osteoarthritis Cartilage Asunto de la revista: ORTOPEDIA / REUMATOLOGIA Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Osteoartritis / Cartílago Articular / Condrocitos / Osteoartritis de la Rodilla / Proteínas Supresoras de Tumor / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Osteoarthritis Cartilage Asunto de la revista: ORTOPEDIA / REUMATOLOGIA Año: 2017 Tipo del documento: Article