Relationship of medial versus superior vocal-cord location of T1 squamous cell carcinoma with tumor recurrence.
Am J Otolaryngol
; 38(3): 316-320, 2017.
Article
en En
| MEDLINE
| ID: mdl-28169008
ABSTRACT
OBJECTIVE:
To determine if the clinical behavior of T1 glottic squamous cell carcinoma varies by its location on the medial free edge or upper aspect of the vocal cords. STUDYDESIGN:
Retrospective cohort.SETTING:
Single tertiary university-affiliated medical center. SUBJECTS ANDMETHODS:
Clinical, treatment, and outcome data were collected for 104 patients with T1N0M0 glottic squamous cell carcinoma who were treated and followed at our center in 1995-2013. Findings were compared between those with a tumor on the medial (n=60, 57.7%) or superior (n=44, 42.3%) aspect of the cords.RESULTS:
Mean follow-up time was 4.15years. No between-group differences were found in demographic or risk factors. There was a significant association of anterior commissure involvement with disease recurrence (P=0.0012) and of superior (vs medial) location with higher rates of anterior commissure involvement (P<0.001) and recurrence (P=0.01) and shorter time to recurrence (P<0.001).CONCLUSIONS:
T1 squamous cell carcinomas on the superior aspect of the vocal cords have a poorer prognosis than medial tumors and should be closely monitored for recurrence.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Pliegues Vocales
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Carcinoma de Células Escamosas
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Neoplasias Laríngeas
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Estroboscopía
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Laringoscopía
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Recurrencia Local de Neoplasia
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Estadificación de Neoplasias
Tipo de estudio:
Incidence_studies
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Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Am J Otolaryngol
Año:
2017
Tipo del documento:
Article