Dried blood spot validation of five immunosuppressants, without hematocrit correction, on two LC-MS/MS systems.

Koster, Remco A; Veenhof, Herman; Botma, Rixt; Hoekstra, Alle Tjipke; Berger, Stefan P; Bakker, Stephan Jl; Alffenaar, Jan-Willem C; Touw, Daan J

Koster, Remco A; Veenhof, Herman; Botma, Rixt; Hoekstra, Alle Tjipke; Berger, Stefan P; Bakker, Stephan Jl; Alffenaar, Jan-Willem C; Touw, Daan J.

Afiliación

Koster RA; University of Groningen, Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.
Veenhof H; University of Groningen, Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.
Botma R; University of Groningen, Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.
Hoekstra AT; University of Groningen, Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.
Berger SP; University of Groningen, Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, The Netherlands.
Bakker SJ; University of Groningen, Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, Groningen, The Netherlands.
Alffenaar JC; University of Groningen, Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.
Touw DJ; University of Groningen, Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen, The Netherlands.

Bioanalysis ; 9(7): 553-563, 2017 Apr.

Article en En | MEDLINE | ID: mdl-28300419

Asunto(s)

Cromatografía Liquida/métodos; Pruebas con Sangre Seca/métodos; Monitoreo de Drogas/métodos; Inmunosupresores/sangre; Espectrometría de Masas en Tándem/métodos; Ciclosporina/sangre; Everolimus/sangre; Hematócrito; Humanos; Ácido Micofenólico/sangre; Sirolimus/sangre; Tacrolimus/sangre

Palabras clave

DBS; clinical validation; cyclosporine A; dried blood spot; everolimus; hematocrit effect; immunosuppressants; mycophenolic acid; sirolimus; tacrolimus

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Cromatografía Liquida / Monitoreo de Drogas / Espectrometría de Masas en Tándem / Pruebas con Sangre Seca / Inmunosupresores Límite: Humans Idioma: En Revista: Bioanalysis Año: 2017 Tipo del documento: Article País de afiliación: Países Bajos

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