Impact of Targeted Interventions on Trends in Central Line-Associated Bloodstream Infection: A Single-Center Experience From the Republic of Korea.
Crit Care Med
; 45(6): e552-e558, 2017 Jun.
Article
en En
| MEDLINE
| ID: mdl-28333762
ABSTRACT
OBJECTIVE:
To assess the impact of targeted interventions on trends in central line-associated bloodstream infection.DESIGN:
A before-and-after study between January 2013 and September 2014.SETTING:
Tertiary hospital in the Republic of Korea. PATIENTS All patients with central-line catheters in the hospital.INTERVENTIONS:
In September 2013, interventions that targeted central line insertion practices were implemented in 10 ICUs, including compliance monitoring with a central line insertion practices bundle and use of an all-inclusive catheter kit. The impact of targeted interventions on trends in central line-associated bloodstream infection was evaluated by segmented autoregression analysis of an interrupted time series. MEASUREMENTS AND MAINRESULTS:
The average hospital-wide central line-associated bloodstream infection rates in the baseline and intervention periods were 1.84 and 1.56 per 1,000 catheter-days, respectively. During the baseline period, there was an increase of central line-associated bloodstream infection rate of 0.12 per 1,000 catheter-days per month. In the intervention period, there was a decrease of central line-associated bloodstream infection rate of 0.16 per 1,000 catheter-days per month (change in slope, -0.28; 95% CI, -0.37 to -0.19; p < 0.0001). In ICUs, the average central line-associated bloodstream infection rates in the baseline and intervention periods were 1.92 and 1.64 per 1,000 catheter-days, respectively. During the baseline period, there was an increase of central line-associated bloodstream infection rate of 0.18 per 1,000 catheter-days per month in ICUs. After sequential-targeted interventions, there was a decrease of central line-associated bloodstream infection rate of 0.16 per 1,000 catheter-days per month (change in slope, -0.34; 95% CI, -0.50 to -0.18; p = 0.0007).CONCLUSIONS:
Targeted interventions were associated with significant changes in trends in the occurrence rate of central line-associated bloodstream infection in ICUs and the entire hospital.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Infección Hospitalaria
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Control de Infecciones
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Infecciones Relacionadas con Catéteres
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Unidades de Cuidados Intensivos
Tipo de estudio:
Guideline
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Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
Crit Care Med
Año:
2017
Tipo del documento:
Article