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Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability.
Stratford, Jeran K; Yan, Feng; Hill, Rebecca A; Major, Michael B; Graves, Lee M; Der, Channing J; Yeh, Jen Jen.
Afiliación
  • Stratford JK; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Yan F; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Hill RA; Department of Cell Biology and Physiology University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Major MB; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Graves LM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Der CJ; Department of Cell Biology and Physiology University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
  • Yeh JJ; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
PLoS One ; 12(4): e0174863, 2017.
Article en En | MEDLINE | ID: mdl-28380042
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteínas Tirosina Quinasas / Proteínas Serina-Treonina Quinasas / Proteínas de Ciclo Celular / Carcinoma Ductal Pancreático / Inestabilidad Cromosómica Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Proteínas Tirosina Quinasas / Proteínas Serina-Treonina Quinasas / Proteínas de Ciclo Celular / Carcinoma Ductal Pancreático / Inestabilidad Cromosómica Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos