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A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis.
Ng, Michael; Thakkar, Dipti; Southam, Lorraine; Werker, Paul; Ophoff, Roel; Becker, Kerstin; Nothnagel, Michael; Franke, Andre; Nürnberg, Peter; Espirito-Santo, Ana Isabel; Izadi, David; Hennies, Hans Christian; Nanchahal, Jagdeep; Zeggini, Eleftheria; Furniss, Dominic.
Afiliación
  • Ng M; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7HE, UK.
  • Thakkar D; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7HE, UK.
  • Southam L; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.
  • Werker P; University of Groningen, University Medical Centre Groningen, Department of Plastic Surgery, Hanzeplein 1, 9713 GZ Groningen, the Netherlands.
  • Ophoff R; UCLA Center for Neurobehavioral Genetics, 695 Charles E. Young Drive South, Los Angeles, CA 90095, USA.
  • Becker K; Cologne Center for Genomics, University of Cologne, Weyertal 115b, 50931 Köln, Germany; Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases, University of Cologne, 50931 Köln, Germany.
  • Nothnagel M; Cologne Center for Genomics, University of Cologne, Weyertal 115b, 50931 Köln, Germany.
  • Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, University Hospital Schleswig-Holstein, 24105 Kiel, Germany.
  • Nürnberg P; Cologne Center for Genomics, University of Cologne, Weyertal 115b, 50931 Köln, Germany; Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases, University of Cologne, 50931 Köln, Germany.
  • Espirito-Santo AI; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7HE, UK.
  • Izadi D; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7HE, UK.
  • Hennies HC; Cologne Center for Genomics, University of Cologne, Weyertal 115b, 50931 Köln, Germany; Cluster of Excellence on Cellular Stress Responses in Aging-associated Diseases, University of Cologne, 50931 Köln, Germany; Department of Biological Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK
  • Nanchahal J; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7HE, UK; Department of Plastic and Reconstructive Surgery, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU
  • Zeggini E; Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.
  • Furniss D; Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Science, University of Oxford, Botnar Research Centre, Windmill Road, Oxford OX3 7HE, UK; Department of Plastic and Reconstructive Surgery, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU
Am J Hum Genet ; 101(3): 417-427, 2017 Sep 07.
Article en En | MEDLINE | ID: mdl-28886342
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fibrosis / Biomarcadores / Polimorfismo de Nucleótido Simple / Contractura de Dupuytren / Estudio de Asociación del Genoma Completo Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fibrosis / Biomarcadores / Polimorfismo de Nucleótido Simple / Contractura de Dupuytren / Estudio de Asociación del Genoma Completo Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies Límite: Humans Idioma: En Revista: Am J Hum Genet Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido