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Crowd Control: E7 Conservation Is the Key to Cancer.
White, Elizabeth A; Munger, Karl.
Afiliación
  • White EA; Department of Otorhinolaryngology, University of Pennsylvania Perelman School of Medicine, 3610 Hamilton Walk, Philadelphia, PA 19104, USA. Electronic address: eawhite@mail.med.upenn.edu.
  • Munger K; Department of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, 150 Harrison Avenue, Boston, MA 02111, USA. Electronic address: karl.munger@tufts.edu.
Cell ; 170(6): 1057-1059, 2017 09 07.
Article en En | MEDLINE | ID: mdl-28886377
ABSTRACT
Several human papillomavirus type 16 (HPV16) oncoproteins contribute to cellular transformation in vitro. In this issue of Cell, Mirabello and colleagues use high-throughput sequencing data to assess the diversity of HPV16 isolates from human patients. These data suggest that the E7 oncoprotein is the fundamental contributor to in vivo carcinogenesis.
Asunto(s)

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Oncogénicas Virales / Papillomavirus Humano 16 Límite: Humans Idioma: En Revista: Cell Año: 2017 Tipo del documento: Article

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Proteínas Oncogénicas Virales / Papillomavirus Humano 16 Límite: Humans Idioma: En Revista: Cell Año: 2017 Tipo del documento: Article