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A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles.
Rebecca, Vito W; Nicastri, Michael C; McLaughlin, Noel; Fennelly, Colin; McAfee, Quentin; Ronghe, Amruta; Nofal, Michel; Lim, Chun-Yan; Witze, Eric; Chude, Cynthia I; Zhang, Gao; Alicea, Gretchen M; Piao, Shengfu; Murugan, Sengottuvelan; Ojha, Rani; Levi, Samuel M; Wei, Zhi; Barber-Rotenberg, Julie S; Murphy, Maureen E; Mills, Gordon B; Lu, Yiling; Rabinowitz, Joshua; Marmorstein, Ronen; Liu, Qin; Liu, Shujing; Xu, Xiaowei; Herlyn, Meenhard; Zoncu, Roberto; Brady, Donita C; Speicher, David W; Winkler, Jeffrey D; Amaravadi, Ravi K.
Afiliación
  • Rebecca VW; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Nicastri MC; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania.
  • McLaughlin N; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Fennelly C; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • McAfee Q; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Ronghe A; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.
  • Nofal M; Department of Chemistry and Integrative Genomics, Princeton University, Princeton, New Jersey.
  • Lim CY; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California.
  • Witze E; Department of Cancer Biology, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Chude CI; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Zhang G; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.
  • Alicea GM; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.
  • Piao S; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Murugan S; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Ojha R; Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Levi SM; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Wei Z; Department of Computer Science, New Jersey Institute of Technology, Newark, New Jersey.
  • Barber-Rotenberg JS; Department of Biochemistry and Biophysics, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Murphy ME; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.
  • Mills GB; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Lu Y; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Rabinowitz J; Department of Chemistry and Integrative Genomics, Princeton University, Princeton, New Jersey.
  • Marmorstein R; Department of Biochemistry and Biophysics, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Liu Q; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.
  • Liu S; Department of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Xu X; Department of Pathology, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Herlyn M; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.
  • Zoncu R; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California.
  • Brady DC; Department of Cancer Biology, Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Speicher DW; Molecular and Cellular Oncogenesis Program and Melanoma Research Center, Wistar Institute, Philadelphia, Pennsylvania.
  • Winkler JD; Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania. ravi.amaravadi@uphs.upenn.edu winkler@sas.upenn.edu.
  • Amaravadi RK; Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania.
Cancer Discov ; 7(11): 1266-1283, 2017 11.
Article en En | MEDLINE | ID: mdl-28899863
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tioléster Hidrolasas / Serina-Treonina Quinasas TOR / Lisosomas / Melanoma / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Revista: Cancer Discov Año: 2017 Tipo del documento: Article
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Tioléster Hidrolasas / Serina-Treonina Quinasas TOR / Lisosomas / Melanoma / Proteínas de la Membrana Límite: Animals / Humans Idioma: En Revista: Cancer Discov Año: 2017 Tipo del documento: Article