DPP4 Inhibition Ameliorates Cardiac Function by Blocking the Cleavage of HMGB1 in Diabetic Mice After Myocardial Infarction.

Sato, Akihiko; Suzuki, Satoshi; Watanabe, Shunsuke; Shimizu, Takeshi; Nakamura, Yuichi; Misaka, Tomofumi; Yokokawa, Tetsuro; Shishido, Tetsuro; Saitoh, Shu-Ichi; Ishida, Takafumi; Kubota, Isao; Takeishi, Yasuchika

Sato, Akihiko; Suzuki, Satoshi; Watanabe, Shunsuke; Shimizu, Takeshi; Nakamura, Yuichi; Misaka, Tomofumi; Yokokawa, Tetsuro; Shishido, Tetsuro; Saitoh, Shu-Ichi; Ishida, Takafumi; Kubota, Isao; Takeishi, Yasuchika.

Afiliación

Sato A; Department of Cardiovascular Medicine, Fukushima Medical University.
Suzuki S; Department of Cardiovascular Medicine, Fukushima Medical University.
Watanabe S; Department of Cardiovascular Medicine, Fukushima Medical University.
Shimizu T; Department of Cardiovascular Medicine, Fukushima Medical University.
Nakamura Y; Department of Cardiovascular Medicine, Fukushima Medical University.
Misaka T; Department of Cardiovascular Medicine, Fukushima Medical University.
Yokokawa T; Department of Cardiovascular Medicine, Fukushima Medical University.
Shishido T; First Department of Internal Medicine, Yamagata University School of Medicine.
Saitoh SI; Department of Cardiovascular Medicine, Fukushima Medical University.
Ishida T; Department of Cardiovascular Medicine, Fukushima Medical University.
Kubota I; First Department of Internal Medicine, Yamagata University School of Medicine.
Takeishi Y; Department of Cardiovascular Medicine, Fukushima Medical University.

Int Heart J ; 58(5): 778-786, 2017 Oct 21.

Article en En | MEDLINE | ID: mdl-28966327

Asunto(s)

Diabetes Mellitus Experimental/complicaciones; Dipeptidil Peptidasa 4/efectos de los fármacos; Proteína HMGB1/biosíntesis; Infarto del Miocardio/metabolismo; Miocardio/metabolismo; Pirimidinas/farmacología; Función Ventricular Izquierda/efectos de los fármacos; Animales; Western Blotting; Dipeptidil Peptidasa 4/metabolismo; Inhibidores de la Dipeptidil-Peptidasa IV/farmacología; Ecocardiografía; Ensayo de Inmunoadsorción Enzimática; Proteína HMGB1/efectos de los fármacos; Masculino; Ratones; Ratones Transgénicos; Infarto del Miocardio/diagnóstico; Infarto del Miocardio/etiología; Miocardio/patología

Palabras clave

Angiogenesis; Diabetes mellitus; Ischemic heart disease

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Pirimidinas / Función Ventricular Izquierda / Dipeptidil Peptidasa 4 / Proteína HMGB1 / Diabetes Mellitus Experimental / Infarto del Miocardio / Miocardio Tipo de estudio: Diagnostic_studies / Etiology_studies Límite: Animals Idioma: En Revista: Int Heart J Asunto de la revista: CARDIOLOGIA Año: 2017 Tipo del documento: Article

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