A new efficient method to monitor precocious puberty nationwide in France.
Eur J Pediatr
; 177(2): 251-255, 2018 Feb.
Article
en En
| MEDLINE
| ID: mdl-28975428
ABSTRACT
Clinical precocious puberty (PP) is a disease, reputed to be on the increase and suspected to be linked to endocrine disrupting chemicals (EDC) exposure. Population-based epidemiological data are lacking in France and scarce elsewhere. We accessed the feasibility of monitoring PP nationwide in France in this context, using a nationwide existing database, the French National Health Insurance Information System. Here, we present the method we used with a step-by-step approach to build and select the most suitable indicator. We built three indicators reflecting the incidence of idiopathic central precocious puberty (ICPP), the most frequent form of PP, and we compared these indicators according to their strengths and weaknesses with respect to surveillance purposes. CONCLUSION:
Monitoring ICPP in France proved feasible using a Drug reimbursement indicator. Our method is cost efficient and highly relevant in public health surveillance. Our step-by-step approach proved helpful to achieve this project and could be proposed for assessing the feasibility of monitoring health outcomes of interest using existing data bases. What is known ⢠Precocious puberty (PP) is suspected to be related to EDC exposure and it is believed to be on the increase in France and in others countries. ⢠Very few epidemiologic data on PP are currently available in the world at the national scale. What is new ⢠This is the first study describing a method to monitor the most frequent form of PP, idiopathic central PP (ICPP) nationwide in a cost-efficient way, using health insurance databases. ⢠This cost-effective method will allow to estimate and monitor the incidence of ICPP in France and to analyze spatial variations at a very precise scale, which will be very useful to examine the role of environmental exposures, especially to EDCs.Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Pubertad Precoz
/
Vigilancia en Salud Pública
Tipo de estudio:
Etiology_studies
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Incidence_studies
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Prognostic_studies
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Risk_factors_studies
Límite:
Child
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Child, preschool
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Female
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Humans
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Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Eur J Pediatr
Año:
2018
Tipo del documento:
Article
País de afiliación:
Francia