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Chromothripsis is linked to TP53 alteration, cell cycle impairment, and dismal outcome in acute myeloid leukemia with complex karyotype.
Rücker, Frank G; Dolnik, Anna; Blätte, Tamara J; Teleanu, Veronica; Ernst, Aurélie; Thol, Felicitas; Heuser, Michael; Ganser, Arnold; Döhner, Hartmut; Döhner, Konstanze; Bullinger, Lars.
Afiliación
  • Rücker FG; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany frank.ruecker@uniklinik-ulm.de.
  • Dolnik A; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany.
  • Blätte TJ; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany.
  • Teleanu V; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany.
  • Ernst A; Division of Molecular Genetics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Thol F; Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Berlin, Germany.
  • Heuser M; Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Berlin, Germany.
  • Ganser A; Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Berlin, Germany.
  • Döhner H; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany.
  • Döhner K; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany.
  • Bullinger L; Department of Internal Medicine III, University Hospital of Ulm, Albert-Einstein-Allee 23, Germany.
Haematologica ; 103(1): e17-e20, 2018 01.
Article en En | MEDLINE | ID: mdl-29079594

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Ciclo Celular / Proteína p53 Supresora de Tumor / Cariotipo Anormal / Cromotripsis Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Haematologica Año: 2018 Tipo del documento: Article País de afiliación: Alemania

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Ciclo Celular / Proteína p53 Supresora de Tumor / Cariotipo Anormal / Cromotripsis Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Haematologica Año: 2018 Tipo del documento: Article País de afiliación: Alemania