Regioselective Halogenation of Arenes and Heterocycles in Hexafluoroisopropanol.
J Org Chem
; 83(2): 930-938, 2018 01 19.
Article
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| MEDLINE
| ID: mdl-29256248
ABSTRACT
Regioselective halogenation of arenes and heterocycles with N-halosuccinimides in fluorinated alcohols is disclosed. Under mild condition reactions, a wide diversity of halogenated arenes are obtained in good yields with high regioselectivity. Additionally, the versatility of the method is demonstrated by the development of one-pot sequential halogenation and halogenation-Suzuki cross-coupling reactions.
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Bases de datos:
MEDLINE
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En
Revista:
J Org Chem
Año:
2018
Tipo del documento:
Article
País de afiliación:
Francia