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Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61.
Calcaterra, Andrea; Iovine, Valentina; Botta, Bruno; Quaglio, Deborah; D'Acquarica, Ilaria; Ciogli, Alessia; Iazzetti, Antonia; Alfonsi, Romina; Lospinoso Severini, Ludovica; Infante, Paola; Di Marcotullio, Lucia; Mori, Mattia; Ghirga, Francesca.
Afiliación
  • Calcaterra A; a Department of Chemistry and Technology of Drugs , Sapienza University of Rome , Rome , Italy.
  • Iovine V; a Department of Chemistry and Technology of Drugs , Sapienza University of Rome , Rome , Italy.
  • Botta B; a Department of Chemistry and Technology of Drugs , Sapienza University of Rome , Rome , Italy.
  • Quaglio D; a Department of Chemistry and Technology of Drugs , Sapienza University of Rome , Rome , Italy.
  • D'Acquarica I; a Department of Chemistry and Technology of Drugs , Sapienza University of Rome , Rome , Italy.
  • Ciogli A; a Department of Chemistry and Technology of Drugs , Sapienza University of Rome , Rome , Italy.
  • Iazzetti A; a Department of Chemistry and Technology of Drugs , Sapienza University of Rome , Rome , Italy.
  • Alfonsi R; b Department of Molecular Medicine , Sapienza University of Rome , Rome , Italy.
  • Lospinoso Severini L; b Department of Molecular Medicine , Sapienza University of Rome , Rome , Italy.
  • Infante P; c Center for Life Nano Science@Sapienza , Istituto Italiano di Tecnologia , Rome , Italy.
  • Di Marcotullio L; b Department of Molecular Medicine , Sapienza University of Rome , Rome , Italy.
  • Mori M; d Pasteur Institute/Cenci Bolognetti Foundation , Sapienza University of Rome , Rome , Italy.
  • Ghirga F; c Center for Life Nano Science@Sapienza , Istituto Italiano di Tecnologia , Rome , Italy.
J Enzyme Inhib Med Chem ; 33(1): 349-358, 2018 Dec.
Article en En | MEDLINE | ID: mdl-29338454

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piridinas / Pirimidinas / Proteínas Hedgehog Límite: Animals Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Piridinas / Pirimidinas / Proteínas Hedgehog Límite: Animals Idioma: En Revista: J Enzyme Inhib Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Italia