Brother's Keeper: Wild-Type Mutant K-Ras Dimers Limit Oncogenesis.
Cell
; 172(4): 645-647, 2018 02 08.
Article
en En
| MEDLINE
| ID: mdl-29425486
ABSTRACT
K-Ras is the undisputed champion of oncogenes, yet our ability to interfere with its oncogenic function is hampered by insufficient mechanistic understanding. In this issue of Cell, Ambrogio and colleagues connect the ability of K-Ras to dimerize to the ability of wild-type K-Ras to limit the oncogenic properties of the mutant.
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Proteínas Proto-Oncogénicas p21(ras)
/
Hermanos
Límite:
Humans
/
Male
Idioma:
En
Revista:
Cell
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos