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Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.
Teslovich, Tanya M; Kim, Daniel Seung; Yin, Xianyong; Stancáková, Alena; Jackson, Anne U; Wielscher, Matthias; Naj, Adam; Perry, John R B; Huyghe, Jeroen R; Stringham, Heather M; Davis, James P; Raulerson, Chelsea K; Welch, Ryan P; Fuchsberger, Christian; Locke, Adam E; Sim, Xueling; Chines, Peter S; Narisu, Narisu; Kangas, Antti J; Soininen, Pasi; Ala-Korpela, Mika; Gudnason, Vilmundur; Musani, Solomon K; Jarvelin, Marjo-Riitta; Schellenberg, Gerard D; Speliotes, Elizabeth K; Kuusisto, Johanna; Collins, Francis S; Boehnke, Michael; Laakso, Markku; Mohlke, Karen L.
Afiliación
  • Teslovich TM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Kim DS; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Yin X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Stancáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland.
  • Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Wielscher M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
  • Naj A; Department of Pathology and Laboratory Medicine, Penn Neurodegeneration Genomics Center, University of Pennsylvania, PA 19104, USA.
  • Perry JRB; Departments of Biostatistics, and Epidemiology (DBE) and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, PA 19104, USA.
  • Huyghe JR; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Davis JP; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Raulerson CK; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Welch RP; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
  • Fuchsberger C; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Chines PS; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA.
  • Narisu N; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Kangas AJ; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.
  • Soininen P; Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland.
  • Ala-Korpela M; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
  • Musani SK; Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland.
  • Jarvelin MR; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
  • Schellenberg GD; Population Health Science, Bristol Medical School, University of Bristol, Bristol, UK.
  • Speliotes EK; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
  • Kuusisto J; Systems Epidemiology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.
  • Collins FS; Department of Epidemiology and Preventive Medicine, Faculty of Medicine, Nursing and Health Sciences, School of Public Health and Preventive Medicine, The Alfred Hospital, Monash University, Melbourne, VIC, Australia.
  • Boehnke M; Icelandic Heart Association and the Faculty of Medicine, University of Iceland, Kopavogur, Iceland.
  • Laakso M; University of Mississippi Medical Center, Jackson, MS 39213, USA.
  • Mohlke KL; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Hum Mol Genet ; 27(9): 1664-1674, 2018 05 01.
Article en En | MEDLINE | ID: mdl-29481666
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Estudio de Asociación del Genoma Completo / Aminoácidos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Estudio de Asociación del Genoma Completo / Aminoácidos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos