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Double positivity for HPV-DNA/p16ink4a is the biomarker with strongest diagnostic accuracy and prognostic value for human papillomavirus related oropharyngeal cancer patients.
Mena, Marisa; Taberna, Miren; Tous, Sara; Marquez, Sandra; Clavero, Omar; Quiros, Beatriz; Lloveras, Belen; Alejo, Maria; Leon, Xavier; Quer, Miquel; Bagué, Silvia; Mesia, Ricard; Nogués, Julio; Gomà, Montserrat; Aguila, Anton; Bonfill, Teresa; Blazquez, Carmen; Guix, Marta; Hijano, Rafael; Torres, Montserrat; Holzinger, Dana; Pawlita, Michael; Pavon, Miguel Angel; Bravo, Ignacio G; de Sanjosé, Silvia; Bosch, Francesc Xavier; Alemany, Laia.
Afiliación
  • Mena M; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain. Electronic address: mmena@iconcologia.net.
  • Taberna M; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Department of Medical Oncology, Catalan Institute of Oncology (ICO), ONCOBELL, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; University of Barcelona, Barcelona, Sp
  • Tous S; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
  • Marquez S; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Clavero O; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
  • Quiros B; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
  • Lloveras B; Department of Pathology, Hospital del Mar, Barcelona, Spain.
  • Alejo M; Department of Pathology, Hospital General de l'Hospitalet, Barcelona, Spain.
  • Leon X; Department of Otorhinolaryngology, Hospital de Sant Pau, Barcelona, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain.
  • Quer M; Department of Otorhinolaryngology, Hospital de Sant Pau, Barcelona, Spain.
  • Bagué S; Department of Pathology, Hospital de Sant Pau, Barcelona, Spain.
  • Mesia R; Department of Medical Oncology, Catalan Institute of Oncology (ICO), ONCOBELL, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; University of Barcelona, Barcelona, Spain; Department of Medical Oncology, Catalan Institute of Oncology (ICO), Badalona, Barcelona, Spain.
  • Nogués J; Department of Otorhinolaryngology, Hospital Universitari Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Gomà M; Department of Pathology, Hospital Universitari Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Aguila A; Department of Otorhinolaryngology, Hospital Universitari Parc Taulí, Sabadell, Barcelona, Spain.
  • Bonfill T; Department of Medical Oncology, Hospital Universitari Parc Taulí, Sabadell, Barcelona, Spain.
  • Blazquez C; Department of Pathology, Hospital Universitari Parc Taulí, Sabadell, Barcelona, Spain.
  • Guix M; Cancer Research Program, IMIM, Hospital del Mar, Barcelona, Spain; Department of Medical Oncology, Hospital del Mar, Barcelona, Spain.
  • Hijano R; Department of Otorhinolaryngology, Hospital del Mar, Barcelona, Spain.
  • Torres M; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Holzinger D; Division of Molecular Diagnostics of Oncogenic Infections, Infection, Inflammation and Cancer Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Pawlita M; Division of Molecular Diagnostics of Oncogenic Infections, Infection, Inflammation and Cancer Program, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Pavon MA; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Bravo IG; Laboratory MIVEGEC (UMR CNRS 5290, IRD 224, UM), French National Center for Scientific Research (CNRS), Montpellier, France.
  • de Sanjosé S; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Epidemiology and Public Health, Centro de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.
  • Bosch FX; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.
  • Alemany L; Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Epidemiology and Public Health, Centro de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. Electroni
Oral Oncol ; 78: 137-144, 2018 03.
Article en En | MEDLINE | ID: mdl-29496041
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ADN Viral / Neoplasias Orofaríngeas / Biomarcadores de Tumor / Inhibidor p16 de la Quinasa Dependiente de Ciclina / Alphapapillomavirus Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Oral Oncol Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: ADN Viral / Neoplasias Orofaríngeas / Biomarcadores de Tumor / Inhibidor p16 de la Quinasa Dependiente de Ciclina / Alphapapillomavirus Tipo de estudio: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Oral Oncol Asunto de la revista: NEOPLASIAS Año: 2018 Tipo del documento: Article