Lysosomal response in relation to &#945;-synuclein pathology differs between Parkinson's disease and multiple system atrophy.

Puska, Gina; Lutz, Mirjam I; Molnar, Kinga; Regelsberger, Günther; Ricken, Gerda; Pirker, Walter; Laszlo, Lajos; Kovacs, Gabor G

Lysosomal response in relation to α-synuclein pathology differs between Parkinson's disease and multiple system atrophy.

Puska, Gina; Lutz, Mirjam I; Molnar, Kinga; Regelsberger, Günther; Ricken, Gerda; Pirker, Walter; Laszlo, Lajos; Kovacs, Gabor G.

Afiliación

Puska G; Department of Anatomy, Cell and Developmental Biology, Eötvös Lorand University, Budapest, Hungary.
Lutz MI; Institute of Neurology, Medical University of Vienna, Vienna, Austria.
Molnar K; Department of Anatomy, Cell and Developmental Biology, Eötvös Lorand University, Budapest, Hungary.
Regelsberger G; Institute of Neurology, Medical University of Vienna, Vienna, Austria.
Ricken G; Institute of Neurology, Medical University of Vienna, Vienna, Austria.
Pirker W; Department of Neurology, Wilhelminenspital, Vienna, Austria.
Laszlo L; Department of Anatomy, Cell and Developmental Biology, Eötvös Lorand University, Budapest, Hungary.
Kovacs GG; Institute of Neurology, Medical University of Vienna, Vienna, Austria. Electronic address: gabor.kovacs@meduniwien.ac.at.

Neurobiol Dis ; 114: 140-152, 2018 06.

Article en En | MEDLINE | ID: mdl-29505813

Asunto(s)

Lisosomas/metabolismo; Lisosomas/patología; Atrofia de Múltiples Sistemas/metabolismo; Atrofia de Múltiples Sistemas/patología; Enfermedad de Parkinson/metabolismo; Enfermedad de Parkinson/patología; alfa-Sinucleína/metabolismo; Anciano; Anciano de 80 o más Años; Femenino; Humanos; Lisosomas/ultraestructura; Masculino; Persona de Mediana Edad; Puente/metabolismo; Puente/patología; Puente/ultraestructura

Palabras clave

Cathepsin D; Endosome; Lysosome; Multiple system atrophy; Neurodegeneration; Parkinson's disease; Prion-like spreading; α-Synuclein

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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Atrofia de Múltiples Sistemas / Alfa-Sinucleína / Lisosomas Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Neurobiol Dis Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Hungria

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