Association between elevated red blood cell distribution width and long-term mortality in acute pulmonary embolism
Turk J Med Sci
; 48(2): 318-323, 2018 Apr 30.
Article
en En
| MEDLINE
| ID: mdl-29714446
ABSTRACT
Background/aim:
The prognostic value of the red cell distribution width (RDW) as a cost-effective and noninvasive test in acute pulmonary embolism (PE) is still unknown. We aimed to investigate the prognostic value of the admission RDW level in the long-term survival of PE patients. Materials andmethods:
In this registry-based, prospective cohort study, a total of 378 patients (mean age 60.4 ± 17.11 years, 47.4% female) who presented with acute PE were enrolled. All the clinical data for each patient were obtained from our institutional PE registry. The follow-up was performed at a median time of 17 months. The primary endpoint was death at follow-up.Results:
The mean RDW in study patients was 14.67 ± 2.13. The all-cause mortality rate during the follow-up was 15.6% (n = 59). After adjustment for potential confounders, the relationship between RDW and long-term mortality showed a trend of a significant level (hazard ratio 1.109; 95% CI, 0.998−1.232; P = 0.053). We divided patients into 3 groups based on the European Society of Cardiology's classification. As we moved from the low risk to the higher risk categories, the mean RDW increased significantly (P = 0.037).Conclusion:
It seems there may be an independent association between RDW at presentation and PE mortality within 17 months.
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MEDLINE
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Turk J Med Sci
Año:
2018
Tipo del documento:
Article