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Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.
Davis, Ryan J; Gönen, Mehmet; Margineantu, Daciana H; Handeli, Shlomo; Swanger, Jherek; Hoellerbauer, Pia; Paddison, Patrick J; Gu, Haiwei; Raftery, Daniel; Grim, Jonathan E; Hockenbery, David M; Margolin, Adam A; Clurman, Bruce E.
Afiliación
  • Davis RJ; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
  • Gönen M; Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
  • Margineantu DH; Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, WA 98195.
  • Handeli S; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR 97239.
  • Swanger J; Department of Industrial Engineering, College of Engineering, Koç University, 34450 Istanbul, Turkey.
  • Hoellerbauer P; School of Medicine, Koç University, 34450 Istanbul, Turkey.
  • Paddison PJ; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
  • Gu H; Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
  • Raftery D; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
  • Grim JE; Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
  • Hockenbery DM; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
  • Margolin AA; Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
  • Clurman BE; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109.
Proc Natl Acad Sci U S A ; 115(21): 5462-5467, 2018 05 22.
Article en En | MEDLINE | ID: mdl-29735700
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Metaboloma / Proteína 7 que Contiene Repeticiones F-Box-WD / Mitocondrias / Mutación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Metaboloma / Proteína 7 que Contiene Repeticiones F-Box-WD / Mitocondrias / Mutación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article