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Poly(2-oxazoline) Hydrogels: State-of-the-Art and Emerging Applications.
Dargaville, Tim R; Park, Jong-Ryul; Hoogenboom, Richard.
Afiliación
  • Dargaville TR; Institute of Health and Biomedical Innovation, Science and Engineering Faculty, Queensland University of Technology, Queensland, 4001, Australia.
  • Park JR; Institute of Health and Biomedical Innovation, Science and Engineering Faculty, Queensland University of Technology, Queensland, 4001, Australia.
  • Hoogenboom R; Supramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Krijgslaan 281 S4, B-9000, Ghent, Belgium.
Macromol Biosci ; 18(6): e1800070, 2018 06.
Article en En | MEDLINE | ID: mdl-29736908
The synthesis of poly(2-oxazoline)s has been known since the 1960s. In the last two decades, they have risen in popularity thanks to improvements in their synthesis and the realization of their potential in the biomedical field due to their "stealth" properties, stimuli responsiveness, and tailorable properties. Even though the bulk of the research to date has been on linear forms of the polymer, they are also of interest for creating network structures due to the relatively easy introduction of reactive functional groups during synthesis that can be cross-linked under a variety of conditions. This opinion article briefly reviews the history of poly(2-oxazoline)s and examines the in vivo data on soluble poly(2-oxazoline)s to date in an effort to predict how hydrogels may perform as implantable materials. This is followed by an overview of the most recent hydrogel synthesis methods and emerging applications, and is concluded with a section on the future directions predicted for these fascinating yet underutilized polymers.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oxazoles / Implantes Experimentales / Hidrogeles Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Macromol Biosci Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Australia

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oxazoles / Implantes Experimentales / Hidrogeles Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Macromol Biosci Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Australia