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Regulation of myeloid cell phagocytosis by LRRK2 via WAVE2 complex stabilization is altered in Parkinson's disease.
Kim, Kwang Soo; Marcogliese, Paul C; Yang, Jungwoo; Callaghan, Steve M; Resende, Virginia; Abdel-Messih, Elizabeth; Marras, Connie; Visanji, Naomi P; Huang, Jana; Schlossmacher, Michael G; Trinkle-Mulcahy, Laura; Slack, Ruth S; Lang, Anthony E; Park, David S.
Afiliación
  • Kim KS; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Marcogliese PC; Brain and Mind Research Institute, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Yang J; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Callaghan SM; Brain and Mind Research Institute, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Resende V; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Abdel-Messih E; Brain and Mind Research Institute, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Marras C; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Visanji NP; Brain and Mind Research Institute, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Huang J; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Schlossmacher MG; Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON K1H 0M5, Canada.
  • Trinkle-Mulcahy L; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Slack RS; Brain and Mind Research Institute, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Lang AE; Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, Toronto, ON M5T 2S8, Canada.
  • Park DS; Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, Toronto, ON M5T 2S8, Canada.
Proc Natl Acad Sci U S A ; 115(22): E5164-E5173, 2018 05 29.
Article en En | MEDLINE | ID: mdl-29760073
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Células Mieloides / Familia de Proteínas del Síndrome de Wiskott-Aldrich / Citofagocitosis / Proteína 2 Quinasa Serina-Treonina Rica en Repeticiones de Leucina Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Enfermedad de Parkinson / Células Mieloides / Familia de Proteínas del Síndrome de Wiskott-Aldrich / Citofagocitosis / Proteína 2 Quinasa Serina-Treonina Rica en Repeticiones de Leucina Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article País de afiliación: Canadá