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Opioid receptor signaling, analgesic and side effects induced by a computationally designed pH-dependent agonist.
Spahn, Viola; Del Vecchio, Giovanna; Rodriguez-Gaztelumendi, Antonio; Temp, Julia; Labuz, Dominika; Kloner, Michael; Reidelbach, Marco; Machelska, Halina; Weber, Marcus; Stein, Christoph.
Afiliación
  • Spahn V; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany.
  • Del Vecchio G; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany.
  • Rodriguez-Gaztelumendi A; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany.
  • Temp J; Department of Drug Discovery and In Vitro Pharmacology, Laboratorios Dr. Esteve, Parc Científic de Barcelona, Barcelona, Spain.
  • Labuz D; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany.
  • Kloner M; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany.
  • Reidelbach M; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany.
  • Machelska H; Freie Universität Berlin, Institute of Theoretical Physics, Arnimallee 14, 14195, Berlin, Germany.
  • Weber M; Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Anesthesiology and Intensive Care Medicine, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany.
  • Stein C; Zuse Institute Berlin, Computational Molecular Design, Takustraße 7, 14195, Berlin, Germany.
Sci Rep ; 8(1): 8965, 2018 06 12.
Article en En | MEDLINE | ID: mdl-29895890
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dolor Postoperatorio / Diseño de Fármacos / Receptores Opioides mu / Analgésicos / Neuralgia Límite: Animals Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Dolor Postoperatorio / Diseño de Fármacos / Receptores Opioides mu / Analgésicos / Neuralgia Límite: Animals Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Alemania