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Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo.
Sharma, Vivek K; Osborn, Maire F; Hassler, Matthew R; Echeverria, Dimas; Ly, Socheata; Ulashchik, Egor A; Martynenko-Makaev, Yury V; Shmanai, Vadim V; Zatsepin, Timofei S; Khvorova, Anastasia; Watts, Jonathan K.
Afiliación
  • Ulashchik EA; Institute of Physical Organic Chemistry , National Academy of Sciences of Belarus , Surganova 13 , 220072 Minsk , Belarus.
  • Martynenko-Makaev YV; Institute of Physical Organic Chemistry , National Academy of Sciences of Belarus , Surganova 13 , 220072 Minsk , Belarus.
  • Shmanai VV; Institute of Physical Organic Chemistry , National Academy of Sciences of Belarus , Surganova 13 , 220072 Minsk , Belarus.
  • Zatsepin TS; Center for Translational Biomedicine , Skolkovo Institute of Science and Technology , Skolkovo , 143026 Moscow , Russia.
  • Khvorova A; Department of Chemistry , Lomonosov Moscow State University , Leninskie gory 1-3 , 119992 Moscow , Russia.
Bioconjug Chem ; 29(7): 2478-2488, 2018 07 18.
Article en En | MEDLINE | ID: mdl-29898368
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Acetilgalactosamina / ARN Interferente Pequeño Límite: Animals Idioma: En Revista: Bioconjug Chem Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Acetilgalactosamina / ARN Interferente Pequeño Límite: Animals Idioma: En Revista: Bioconjug Chem Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article