Common SVOCs in house dust from urban dwellings with schoolchildren in six typical cities of China and associated non-dietary exposure and health risk assessment.
Environ Int
; 120: 431-442, 2018 11.
Article
en En
| MEDLINE
| ID: mdl-30138888
ABSTRACT
This paper presents concentrations of common SVOCs in house dusts from urban dwellings with schoolchildren in six typical Chinese cities in winter and summer. Among the detected SVOCs, DBP and DEHP have a higher detection rate. The levels of these two substances contribute an average proportion of over 90% of the total SVOCs' levels, and show a significant correlation in most cities. Based on measured concentrations, schoolchildren's non-dietary exposures to DBP and DEHP at homes are estimated. Due to a longer time spent in child's bedrooms, children's non-dietary exposures to phthalates in child's bedrooms are greatly higher than that in living rooms. As for DBP non-dietary exposure, the most significant pathway is dermal absorption from air, accounting for >70%, whereas, the most predominant pathway for DEHP non-dietary exposure is dust ingestion, contributing from 61.5% to 91.9%. Based on estimated exposure doses, child-specific reproductive and cancer risk are assessed by comparing the exposure doses with DBP and DEHP benchmarks specified in California's Proposition 65. Owing to the high DBP exposure, nearly all of target schoolchildren appear to have a severe reproductive risk, although only non-dietary exposures at home are considered in this study. The average risk quotient of DBP exposure for child-specific MADL in all cities is 31.27 in winter and 10.35 in summer. Also, some schoolchildren are confronted with potential carcinogenic risk, because DEHP exposure exceeds child-specific NSRLs. The maximum DEHP exposure exceeds the cancer benchmark by over 6 times. These results also indicate that controlling indoor phthalates pollution at home is urgent to ensure the healthy development of children in China.
Palabras clave
Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Ácidos Ftálicos
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Contaminación del Aire Interior
/
Polvo
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Exposición a Riesgos Ambientales
/
Contaminantes Ambientales
/
Compuestos Orgánicos Volátiles
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Child
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Female
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Humans
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Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
Environ Int
Año:
2018
Tipo del documento:
Article
País de afiliación:
China