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Performance of the COMPASS-31 questionnaire with regard to autonomic nervous system testing results and medication use: a prospective study in a real-life setting.
Ruska, Berislav; Pavicic, Tin; Pavlovic, Ivan; Junakovic, Anamari; Adamec, Ivan; Crnosija, Luka; Krbot Skoric, Magdalena; Habek, Mario.
Afiliación
  • Ruska B; School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Pavicic T; School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Pavlovic I; School of Medicine, University of Zagreb, Zagreb, Croatia.
  • Junakovic A; Referral Center for Autonomic Nervous System Disorders, Department of Neurology, University Hospital Center Zagreb, Kispaticeva 12, HR-10000, Zagreb, Croatia.
  • Adamec I; Referral Center for Autonomic Nervous System Disorders, Department of Neurology, University Hospital Center Zagreb, Kispaticeva 12, HR-10000, Zagreb, Croatia.
  • Crnosija L; Referral Center for Autonomic Nervous System Disorders, Department of Neurology, University Hospital Center Zagreb, Kispaticeva 12, HR-10000, Zagreb, Croatia.
  • Krbot Skoric M; Referral Center for Autonomic Nervous System Disorders, Department of Neurology, University Hospital Center Zagreb, Kispaticeva 12, HR-10000, Zagreb, Croatia.
  • Habek M; Faculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, Croatia.
Neurol Sci ; 39(12): 2079-2084, 2018 Dec.
Article en En | MEDLINE | ID: mdl-30140988
ABSTRACT
The aim of this study was to investigate the performance of the Composite Autonomic System Score-31 (COMPASS-31) questionnaire in a real-life setting in consecutive patients referred to the laboratory for objective testing of the autonomic nervous system (ANS), with the hypothesis that COMPASS-31 results differ depending on medications and findings of the tilt table test results. One hundred seventy-one consecutive patients (125 females, mean age 41.5 ± 19.3) referred for testing of the ANS were enrolled. Before testing, all patients completed the recently validated Croatian version of COMPASS-31. The following data were systematically collected for all patients age, sex, diagnoses, and medications. Results of COMPASS-31 were significantly higher in patients taking medications with a known influence on the ANS (p < 0.001). Patients with postural orthostatic tachycardia had significantly higher orthostatic intolerance and vasomotor domains of COMPASS-31 (p = 0.048 and p = 0.022, respectively). Patients with a cardiovagal score ≥ 1 had a significantly higher vasomotor domain of COMPASS-31 compared to patients with normal results of ANS tests (p = 0.030). These findings suggest the COMPASS-31 might be a valuable screening tool for autonomic dysfunctions, as it is associated with impaired ANS tests, but usage of medications that modify the ANS should always be taken into account.
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sistema Nervioso Autónomo / Enfermedades del Sistema Nervioso Autónomo / Encuestas y Cuestionarios Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Neurol Sci Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Croacia

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Sistema Nervioso Autónomo / Enfermedades del Sistema Nervioso Autónomo / Encuestas y Cuestionarios Tipo de estudio: Observational_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Neurol Sci Asunto de la revista: NEUROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Croacia