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Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis.
Sode, Jacob; Bank, Steffen; Vogel, Ulla; Andersen, Paal Skytt; Sørensen, Signe Bek; Bojesen, Anders Bo; Andersen, Malene Rohr; Brandslund, Ivan; Dessau, Ram Benny; Hoffmann, Hans Jürgen; Glintborg, Bente; Hetland, Merete Lund; Locht, Henning; Heegaard, Niels Henrik; Andersen, Vibeke.
Afiliación
  • Sode J; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.
  • Bank S; Department of Autoimmunology and Biomarkers, Statens Serum Institut, Copenhagen, Denmark.
  • Vogel U; Department of Rheumatology, Frederiksberg Hospital, Frederiksberg, Denmark.
  • Andersen PS; Department of Rheumatology, Skåne University Hospital, Lund, Sweden.
  • Sørensen SB; Focused Research Unit for Molecular Diagnostic and Clinical Research, Hospital of Southern Jutland, Aabenraa, Denmark. stb@mb.au.dk.
  • Bojesen AB; Medical Department, Viborg Regional Hospital, Viborg, Denmark. stb@mb.au.dk.
  • Andersen MR; National Research Centre for the Working Environment, Copenhagen, Denmark.
  • Brandslund I; Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark.
  • Dessau RB; Veterinary Disease Biology, University of Copenhagen, Copenhagen, Denmark.
  • Hoffmann HJ; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.
  • Glintborg B; Focused Research Unit for Molecular Diagnostic and Clinical Research, Hospital of Southern Jutland, Aabenraa, Denmark.
  • Hetland ML; Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
  • Locht H; Focused Research Unit for Molecular Diagnostic and Clinical Research, Hospital of Southern Jutland, Aabenraa, Denmark.
  • Heegaard NH; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Hellerup, Denmark.
  • Andersen V; Department of Biochemistry, Hospital of Lillebaelt, Vejle, Denmark.
BMC Med Genet ; 19(1): 165, 2018 09 12.
Article en En | MEDLINE | ID: mdl-30208882

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Espondilitis Anquilosante / Transducción de Señal / FN-kappa B / Factor de Necrosis Tumoral alfa / Predisposición Genética a la Enfermedad / Interleucina-17 / Interleucina-23 Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: BMC Med Genet Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Dinamarca

Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Espondilitis Anquilosante / Transducción de Señal / FN-kappa B / Factor de Necrosis Tumoral alfa / Predisposición Genética a la Enfermedad / Interleucina-17 / Interleucina-23 Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged País/Región como asunto: Europa Idioma: En Revista: BMC Med Genet Asunto de la revista: GENETICA MEDICA Año: 2018 Tipo del documento: Article País de afiliación: Dinamarca