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Blocking HIF signaling via novel inhibitors of CA9 and APE1/Ref-1 dramatically affects pancreatic cancer cell survival.
Logsdon, Derek P; Shah, Fenil; Carta, Fabrizio; Supuran, Claudiu T; Kamocka, Malgorzata; Jacobsen, Max H; Sandusky, George E; Kelley, Mark R; Fishel, Melissa L.
Afiliación
  • Logsdon DP; Indiana University School of Medicine, Department of Pharmacology and Toxicology, Indianapolis, IN, USA.
  • Shah F; Indiana University School of Medicine, Department of Pediatrics, Wells Center for Pediatric Research, Indianapolis, IN, USA.
  • Carta F; University of Florence, Neurofarba Department, Section of Medicinal Chemistry, Florence, Italy.
  • Supuran CT; University of Florence, Neurofarba Department, Section of Medicinal Chemistry, Florence, Italy.
  • Kamocka M; Indiana University School of Medicine, Department of Nephrology, Indianapolis, IN, USA.
  • Jacobsen MH; Indiana University School of Medicine, Department of Pathology and Laboratory Medicine, Indianapolis, IN, USA.
  • Sandusky GE; Indiana University School of Medicine, Department of Pathology and Laboratory Medicine, Indianapolis, IN, USA.
  • Kelley MR; Indiana University School of Medicine, Department of Pharmacology and Toxicology, Indianapolis, IN, USA.
  • Fishel ML; Indiana University School of Medicine, Department of Pediatrics, Wells Center for Pediatric Research, Indianapolis, IN, USA.
Sci Rep ; 8(1): 13759, 2018 09 13.
Article en En | MEDLINE | ID: mdl-30214007
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / ADN-(Sitio Apurínico o Apirimidínico) Liasa / Subunidad alfa del Factor 1 Inducible por Hipoxia / Anhidrasa Carbónica IX / Antígenos de Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / ADN-(Sitio Apurínico o Apirimidínico) Liasa / Subunidad alfa del Factor 1 Inducible por Hipoxia / Anhidrasa Carbónica IX / Antígenos de Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos