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Resolving power in liquid chromatography: A trade-off between efficiency and analysis time.
Dores-Sousa, José Luís; De Vos, Jelle; Eeltink, Sebastiaan.
Afiliación
  • Dores-Sousa JL; Department of Chemical Engineering, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
  • De Vos J; Department of Chemical Engineering, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
  • Eeltink S; Department of Chemical Engineering, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
J Sep Sci ; 42(1): 38-50, 2019 Jan.
Article en En | MEDLINE | ID: mdl-30240528
This review describes chromatographic dispersion and different plate-height models frequently used to assess the chromatographic performance of ultra-high-pressure liquid chromatography column technology. Furthermore, different performance indices, including the resolution, the separation impedance, and kinetic plots are discussed allowing to quantify and visualize the resolving power in liquid chromatography. The construction of kinetic plots is explained, and different visualization approaches are highlighted. Finally, key instrument and column-technology developments to advance the kinetic performance limits are discussed and selected state-of-the-art applications are highlighted.
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Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: J Sep Sci Año: 2019 Tipo del documento: Article País de afiliación: Bélgica

Texto completo: 1 Bases de datos: MEDLINE Idioma: En Revista: J Sep Sci Año: 2019 Tipo del documento: Article País de afiliación: Bélgica