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Once-weekly prophylaxis with 40 IU/kg nonacog beta pegol (N9-GP) achieves trough levels of >15% in patients with haemophilia B: Pooled data from the paradigm™ trials.
Oldenburg, Johannes; Carcao, Manuel; Lentz, Steven R; Mahlangu, Johnny; Mancuso, Maria Elisa; Matsushita, Tadashi; Négrier, Claude; Clausen, Wan Hui Ong; Ehrenforth, Silke; Young, Guy.
Afiliación
  • Oldenburg J; Institute of Experimental Haematology and Transfusion Medicine, University Clinic Bonn, Bonn, Germany.
  • Carcao M; Division of Haematology/Oncology, Department of Paediatrics and Research Institute, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
  • Lentz SR; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa.
  • Mahlangu J; Haemophilia Comprehensive Care Centre, Faculty of Health Sciences, NHLS and University of the Witwatersrand, Johannesburg, South Africa.
  • Mancuso ME; Angelo Bianchi Bonomi Haemophilia and Thrombosis Centre, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
  • Matsushita T; Department of Transfusion Medicine, Nagoya University Hospital, Nagoya, Japan.
  • Négrier C; Haemophilia and Thrombosis Centre, Louis Pradel Hospital, University Claude Bernard, Lyon, France.
  • Clausen WHO; Novo Nordisk A/S, Søborg, Denmark.
  • Ehrenforth S; Novo Nordisk A/S, Søborg, Denmark.
  • Young G; Hemostasis and Thrombosis Center, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, California.
Haemophilia ; 24(6): 911-920, 2018 Nov.
Article en En | MEDLINE | ID: mdl-30248217
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polietilenglicoles / Factor IX / Hemofilia B / Hemorragia Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: Haemophilia Asunto de la revista: HEMATOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Polietilenglicoles / Factor IX / Hemofilia B / Hemorragia Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Idioma: En Revista: Haemophilia Asunto de la revista: HEMATOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Alemania