Photoredox/Nickel-Catalyzed Single-Electron Tsuji-Trost Reaction: Development and Mechanistic Insights.
Angew Chem Int Ed Engl
; 57(48): 15847-15851, 2018 11 26.
Article
en En
| MEDLINE
| ID: mdl-30307672
ABSTRACT
A regioselective, nickel-catalyzed photoredox allylation of secondary, benzyl, and α-alkoxy radical precursors is disclosed. Through this manifold, a variety of linear allylic alcohols and allylated monosaccharides are accessible in high yields under mild reaction conditions. Quantum mechanical calculations [DFT and DLPNO-CCSD(T)] support the mechanistic hypothesis of a Ni0 to NiII oxidative addition pathway followed by radical addition and inner-sphere allylation.
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Texto completo:
1
Bases de datos:
MEDLINE
Asunto principal:
Propanoles
/
Electrones
/
Níquel
Idioma:
En
Revista:
Angew Chem Int Ed Engl
Año:
2018
Tipo del documento:
Article
País de afiliación:
Estados Unidos