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Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer.
Singh, Vishal; Yeoh, Beng San; Chassaing, Benoit; Xiao, Xia; Saha, Piu; Aguilera Olvera, Rodrigo; Lapek, John D; Zhang, Limin; Wang, Wei-Bei; Hao, Sijie; Flythe, Michael D; Gonzalez, David J; Cani, Patrice D; Conejo-Garcia, Jose R; Xiong, Na; Kennett, Mary J; Joe, Bina; Patterson, Andrew D; Gewirtz, Andrew T; Vijay-Kumar, Matam.
Afiliación
  • Singh V; UT-Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.
  • Yeoh BS; Graduate Program in Immunology and Infectious Diseases, Pennsylvania State University, State College, PA 16802, USA.
  • Chassaing B; Neuroscience Institute, Georgia State University, Atlanta, GA 30303, USA; Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
  • Xiao X; Department of Nutritional Sciences, Pennsylvania State University, State College, PA 16802, USA.
  • Saha P; UT-Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.
  • Aguilera Olvera R; Department of Nutritional Sciences, Pennsylvania State University, State College, PA 16802, USA.
  • Lapek JD; Department of Pharmacology, University of California, San Diego, CA 92093, USA.
  • Zhang L; Department of Veterinary and Biomedical Sciences, Pennsylvania State University, State College, PA 16802, USA; CAS and State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan, China.
  • Wang WB; Department of Veterinary and Biomedical Sciences, Pennsylvania State University, State College, PA 16802, USA.
  • Hao S; Department of Biomedical Engineering, Pennsylvania State University, State College, PA 16802, USA.
  • Flythe MD; USDA-Agriculture Research Service, University of Kentucky, Lexington, KY 40546, USA.
  • Gonzalez DJ; Department of Pharmacology, University of California, San Diego, CA 92093, USA.
  • Cani PD; WELBIO (Walloon Excellence in Life Sciences and Biotechnology), Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium.
  • Conejo-Garcia JR; Department of Immunology, H. Lee Moffitt Cancer Center, Tampa, FL 33612, USA.
  • Xiong N; Department of Veterinary and Biomedical Sciences, Pennsylvania State University, State College, PA 16802, USA.
  • Kennett MJ; Department of Veterinary and Biomedical Sciences, Pennsylvania State University, State College, PA 16802, USA.
  • Joe B; UT-Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA.
  • Patterson AD; Department of Veterinary and Biomedical Sciences, Pennsylvania State University, State College, PA 16802, USA.
  • Gewirtz AT; Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA.
  • Vijay-Kumar M; UT-Microbiome Consortium, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA; Department of Medical Microbiology and Immunology, University of Toledo, Toledo, OH 43614, USA. Electronic address: matamvijay.kumar@utoledo.edu.
Cell ; 175(3): 679-694.e22, 2018 10 18.
Article en En | MEDLINE | ID: mdl-30340040
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fibras de la Dieta / Colestasis / Carcinoma Hepatocelular / Fermentación / Disbiosis / Microbioma Gastrointestinal / Neoplasias Hepáticas Límite: Animals Idioma: En Revista: Cell Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Fibras de la Dieta / Colestasis / Carcinoma Hepatocelular / Fermentación / Disbiosis / Microbioma Gastrointestinal / Neoplasias Hepáticas Límite: Animals Idioma: En Revista: Cell Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos