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Potent Antiglioblastoma Agents by Hybridizing the Onium-Alkyloxy-Stilbene Based Structures of an α7-nAChR, α9-nAChR Antagonist and of a Pro-Oxidant Mitocan.
Bavo, Francesco; Pucci, Susanna; Fasoli, Francesca; Lammi, Carmen; Moretti, Milena; Mucchietto, Vanessa; Lattuada, Donatella; Viani, Paola; De Palma, Clara; Budriesi, Roberta; Corradini, Irene; Dowell, Cheryl; McIntosh, J Michael; Clementi, Francesco; Bolchi, Cristiano; Gotti, Cecilia; Pallavicini, Marco.
Afiliación
  • Bavo F; Dipartimento di Scienze Farmaceutiche , Università degli Studi di Milano , Via Mangiagalli 25 , I-20133 Milano , Italy.
  • Pucci S; Institute of Neuroscience , CNR , Via Vanvitelli 32 , I-20129 Milano , Italy.
  • Fasoli F; Hunimed University , Via Rita Levi-Montalcini 4 , 20090 Pieve Emanuele (MI) , Italy.
  • Lammi C; Institute of Neuroscience , CNR , Via Vanvitelli 32 , I-20129 Milano , Italy.
  • Moretti M; Dipartimento di Scienze Farmaceutiche , Università degli Studi di Milano , Via Mangiagalli 25 , I-20133 Milano , Italy.
  • Mucchietto V; Institute of Neuroscience , CNR , Via Vanvitelli 32 , I-20129 Milano , Italy.
  • Lattuada D; Department of Medical Biotechnology and Translational Medicine , Università degli Studi di Milano , Via Vanvitelli 32 , I-20129 Milano , Italy.
  • Viani P; Institute of Neuroscience , CNR , Via Vanvitelli 32 , I-20129 Milano , Italy.
  • De Palma C; Department of Medical Biotechnology and Translational Medicine , Università degli Studi di Milano , Via Vanvitelli 32 , I-20129 Milano , Italy.
  • Budriesi R; Department of Medical Biotechnology and Translational Medicine , Università degli Studi di Milano , Via Vanvitelli 32 , I-20129 Milano , Italy.
  • Corradini I; Unit of Clinical Pharmacology , University Hospital "Luigi Sacco"-ASST Fatebenefratelli Sacco , Via G. B. Grassi 74 , I-20157 Milano , Italy.
  • Dowell C; Dipartimento di Farmacia e Biotecnologie , Università degli Studi di Bologna , Via Belmeloro 6 , I-40126 Bologna , Italy.
  • McIntosh JM; Institute of Neuroscience , CNR , Via Vanvitelli 32 , I-20129 Milano , Italy.
  • Clementi F; Department of Biology , University of Utah , 257S.1400 East , Salt Lake City , Utah 84112 , United States.
  • Bolchi C; Department of Biology , University of Utah , 257S.1400 East , Salt Lake City , Utah 84112 , United States.
  • Gotti C; George E. Wahlen Veterans Affairs Medical Center , 500 Foothill Drive , Salt Lake City , Utah 84148 , United States.
  • Pallavicini M; Department of Psychiatry , University of Utah , 501 Chipeta Way , Salt Lake City , Utah 84108 , United States.
J Med Chem ; 61(23): 10531-10544, 2018 12 13.
Article en En | MEDLINE | ID: mdl-30403486
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Estilbenos / Receptores Nicotínicos / Especies Reactivas de Oxígeno / Glioblastoma / Receptor Nicotínico de Acetilcolina alfa 7 Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Estilbenos / Receptores Nicotínicos / Especies Reactivas de Oxígeno / Glioblastoma / Receptor Nicotínico de Acetilcolina alfa 7 Límite: Humans Idioma: En Revista: J Med Chem Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Italia