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STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial.
Reilley, Matthew J; McCoon, Patricia; Cook, Carl; Lyne, Paul; Kurzrock, Razelle; Kim, Youngsoo; Woessner, Richard; Younes, Anas; Nemunaitis, John; Fowler, Nathan; Curran, Michael; Liu, Qinying; Zhou, Tianyuan; Schmidt, Joanna; Jo, Minji; Lee, Samantha J; Yamashita, Mason; Hughes, Steven G; Fayad, Luis; Piha-Paul, Sarina; Nadella, Murali V P; Xiao, Xiaokun; Hsu, Jeff; Revenko, Alexey; Monia, Brett P; MacLeod, A Robert; Hong, David S.
Afiliación
  • Reilley MJ; Division of Hematology/Oncology, University of Virginia Health System, Charlottesville, VA, USA.
  • McCoon P; Oncology, IMED Biotech Unit, AstraZeneca Pharmaceuticals, Waltham, MA, USA.
  • Cook C; Oncology, IMED Biotech Unit, AstraZeneca Pharmaceuticals, Waltham, MA, USA.
  • Lyne P; Oncology, IMED Biotech Unit, AstraZeneca Pharmaceuticals, Waltham, MA, USA.
  • Kurzrock R; UC San Diego Moores Cancer Center, La Jolla, CA, USA.
  • Kim Y; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Woessner R; Oncology, IMED Biotech Unit, AstraZeneca Pharmaceuticals, Waltham, MA, USA.
  • Younes A; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Nemunaitis J; Mary Crowley Cancer Research Center, Dallas, TX, USA.
  • Fowler N; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0455, Houston, TX, 77030, USA.
  • Curran M; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0455, Houston, TX, 77030, USA.
  • Liu Q; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0455, Houston, TX, 77030, USA.
  • Zhou T; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Schmidt J; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Jo M; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Lee SJ; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Yamashita M; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Hughes SG; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Fayad L; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0455, Houston, TX, 77030, USA.
  • Piha-Paul S; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0455, Houston, TX, 77030, USA.
  • Nadella MVP; Drug Safety and Metabolism, IMED Biotech Unit, AstraZeneca Pharmaceuticals, Waltham, MA, USA.
  • Xiao X; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Hsu J; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Revenko A; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Monia BP; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • MacLeod AR; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Inc., Carlsbad, CA, USA.
  • Hong DS; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 0455, Houston, TX, 77030, USA. dshong@mdanderson.org.
J Immunother Cancer ; 6(1): 119, 2018 11 16.
Article en En | MEDLINE | ID: mdl-30446007
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oligonucleótidos / Oligonucleótidos Antisentido / Linfoma Tipo de estudio: Clinical_trials Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Immunother Cancer Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Bases de datos: MEDLINE Asunto principal: Oligonucleótidos / Oligonucleótidos Antisentido / Linfoma Tipo de estudio: Clinical_trials Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: J Immunother Cancer Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos